Treatment Trials

1 Clinical Trials for Various Conditions

TERMINATED

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Description

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of INCB099318 in select solid tumors.

Conditions

Advanced Solid Tumors MSI-H/dMMR Tumors Cutaneous Squamous Cell Carcinoma Urothelial Carcinoma, HCC Cervical Cancer Esophageal Squamous Cell Carcinoma Merkel Cell Carcinoma Small-cell Lung Cancer Mesothelioma PD-L1 Amplified Tumor (9p24.1)Nasopharyngeal Carcinoma Cyclin-dependent Kinase 12 Mutated Tumors Basal Cell Carcinoma (Unresectable or Metastatic)Sarcomatoid Renal Cell Carcinoma Clear Cell Ovarian or Endometrial Carcinoma Anal Carcinoma Squamous Cell Penile Carcinoma DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)