6 Clinical Trials for Various Conditions
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
Acamprosate will be given to approximately 30 DUI Court participants for 3 months and outcomes will be monitored. The hypothesis is that acamprosate will be safe and well-tolerated and that subjects' craving and other symptoms related to addiction will improve over time.
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator. Subjects will be administered marijuana of varying pre-determined concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) during 3 of the visits and alcohol during one of the visits. Throughout the duration of each visit, brain activity will be measured noninvasively using an electroencephalogram (EEG) headset. The purpose of this study is to: 1. Further understand the effects of acute cannabis intoxication on driving performance in a driving simulator 2. Develop and refine brain-based biomarkers of impairment due to acute cannabis intoxication