Treatment Trials

3 Clinical Trials for Various Conditions

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      COMPLETED
      Study Confirming A Human Challenge Model and Investigating The Safety Of VLA1701
      Description

      This is a single-center, double-blind, placebo-controlled, Phase II vaccination and challenge study designed to confirm a human challenge model with E. coli strain LSN03-016011/A.

      Conditions
      Enterotoxigenic Escherichia Coli InfectionDiarrhea
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      COMPLETED
      Shigella CVD 31000: Study of Responses with Shigella-ETEC Vaccine Strain CVD 1208S-122
      Description

      The purpose of this study is to determine whether a live, oral, combined Shigella-ETEC vaccine candidate, known as strain CVD 1208S-122, is safe and immunogenic.

      Conditions
      Shigella InfectionEnterotoxigenic Escherichia Coli Infection
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      RECRUITING
      Phase 1, Randomized, Placebo-Controlled, Blinded Study in Healthy Adults Challenged with Enterotoxigenic Escherichia Coli, of the Safety, Tolerability and Anti-Diarrheal Activity of VENBETA6890, an Orally Administered, Human Monoclonal IgA
      Description

      This is a phase 1, randomized, placebo-controlled, blinded study in up to 36 healthy adults, aged 18-45 years, challenged with Enterotoxigenic Escherichia coli, evaluating the safety, tolerability and anti-diarrheal activity of VENBETA6890, an orally administered, human monoclonal IgA.

      Conditions
      Diarrhea Infectious
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