Treatment Trials

2 Clinical Trials for Various Conditions

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      RECRUITING
      Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans
      Description

      ActivSight™ combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery. A small adaptor that fits between any existing laparoscope and camera systems and a separate light source placed along any current commercial system will deliver objective real-time tissue perfusion and blood flow information intraoperatively. Primary Objective: To determine the feasibility of ActivSight™ in detecting and displaying tissue perfusion and blood flow in the conduit and foregut anastomoses in esophageal resection/reconstructive surgery. The investigators will compare the precision and accuracy among the naked eye inspection, ICG and LSCI in assessing the vascularity of the conduit.

      Conditions
      Esophagus CancerEsophageal CancerEsophageal NeoplasmsEsophageal DiseasesEsophageal AdenocarcinomaEsophageal Squamous Cell CarcinomaEsophagus SCCEsophagus TumorEsophagus AdenocarcinomaEsophagus Neoplasm
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      COMPLETED
      Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors
      Description

      The purpose of the trial is to establish the tolerability of HuMax-TF-ADC in a mixed population of patients with specified solid tumors.

      Conditions
      Ovary CancerCervix CancerEndometrium CancerBladder CancerProstate Cancer (CRPC)Esophagus CancerLung Cancer(NSCLC)Squamous Cell Carcinoma of the Head and Neck (SCCHN)
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