Treatment Trials

2 Clinical Trials for Various Conditions

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      COMPLETED
      ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)
      Description

      The purpose of this study was to evaluate the safety and efficacy of revusiran (ALN-TTRSC) in patients with transthyretin (TTR) mediated Familial Amyloidotic Cardiomyopathy. Dosing has been discontinued; patients are being followed-up for safety.

      Conditions
      Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)Amyloidosis, HereditaryAmyloid Neuropathies, FamilialAmyloid NeuropathiesAmyloidosis, Hereditary, Transthyretin-RelatedFamilial Transthyretin Cardiac Amyloidosis
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      COMPLETED
      DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis
      Description

      The purpose of this study is to characterize the frequency of TTR mutations in subjects suspected of having cardiac amyloidosis

      Conditions
      Familial Amyloidotic Cardiomyopathy (FAC)
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