Treatment Trials

3 Clinical Trials for Various Conditions

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      COMPLETED
      A Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet in Healthy Adult Subjects
      Description

      The purpose of this study is to determine the relative bioavailability of ASP015K under fasting conditions after single-dose administration between a test-tablet formulation and a reference-tablet formulation. This study will also evaluate the food effect on bioavailability of the test formulation, and evaluate the safety and tolerability after single-dose administration of the test- and reference-tablet formulations.

      Conditions
      Bioavailability of ASP015KHealthy SubjectsPharmacokinetics of ASP015KFood Effect of ASP015K
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      COMPLETED
      A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K
      Description

      The purpose of this study is to compare the pharmacokinetics (PK) profiles of three different strengths of ASP015K extended release formulation and an immediate release formulation and to evaluate food effect on extended release strengths in healthy volunteers.

      Conditions
      Pharmacokinetics of ASP015KFood EffectHealthy Volunteers
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      COMPLETED
      A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation
      Description

      The purpose of this study is to determine the bioavailability and pharmacokinetics between two different formulations of ASP015K tablets and determine the food effect on the absorption of the new formulation.

      Conditions
      Pharmacokinetics of ASP015KBioavailability of ASP015KHealthy Subjects
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