Treatment Trials

3 Clinical Trials for Various Conditions

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      TERMINATED
      EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN)
      Description

      This is a randomized, double-masked, multicenter, study to evaluate the efficacy, safety, and tolerability of IRX-101 versus 5% povidone-iodine (PI) in subjects receiving intravitreal anti-VEGF injections. The study will be conducted in up to 30 centers in the United States (US).

      Conditions
      Diabetic Macular EdemaBranch Retinal Vein OcclusionGlaucoma/Closed Angle Glaucoma
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      COMPLETED
      Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)
      Description

      This study will assess any side effects that may occur when QPI-1007 is injected into the eye in subjects with acute primary angle-closure glaucoma, as well as how long it takes for the body to clear the drug. This study will also test whether QPI-1007, injected into the eye, helps prevent both structural damage of the nerve tissue in the eye and the loss of visual function in subjects with acute primary angle-closure glaucoma.

      Conditions
      Glaucoma, Angle-closure, Primary, Acute
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      COMPLETED
      Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach
      Description

      To measure surgical success of open vs closed conjunctiva with Xen implantation.

      Conditions
      Glaucoma, Open-Angle
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