Treatment Trials

2 Clinical Trials for Various Conditions

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      RECRUITING
      Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
      Description

      This is an open-label extension study to evaluate the long-term efficacy, safety and tolerability of iptacopan in subjects with C3 glomerulopathy or idiopathic immune-complex-membranoproliferative glomerulonephritis

      Conditions
      C3 GlomerulopathyIdiopathic Immune-complex-membranoproliferative Glomerulonephritis
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      TERMINATED
      A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471
      Description

      The primary purpose of this study was to evaluate the efficacy of 12 months of oral ACH-0144471 (also known as danicopan and ALXN2040) in participants with C3G or IC-MPGN based on histologic scoring and proteinuria.

      Conditions
      C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative GlomerulonephritisIC-MPGNDense Deposit Disease
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