Treatment Trials

2 Clinical Trials for Various Conditions

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      TERMINATED
      Efficacy and Safety of Riociguat in Patients With Symptomatic Pulmonary Hypertension (PH) Associated With Idiopathic Interstitial Pneumonias (IIP)
      Description

      To evaluate the efficacy and safety of 26-weeks of treatment with riociguat vs. placebo in patients with symptomatic PH (pulmonary hypertension) associated with IIP (idiopathic interstitial pneumonias).

      Conditions
      Idiopathic Interstitial Pneumonias / Hypertension,Pulmonary
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      COMPLETED
      Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT
      Description

      This study assesses the safety and efficacy of bardoxolone methyl relative to placebo in patients with pulmonary hypertension to determine the recommended dose range, evaluate the change from baseline in 6-minute walk distance (6MWD) and determine the effect of Bardoxolone methyl in pulmonary hypertension associated with connective tissue disease, interstitial lung disease, and idiopathic etiologies, including subsets of patients with WHO Group III or WHO Group V PH following 16 weeks of study participation.

      Conditions
      Pulmonary Arterial HypertensionPulmonary HypertensionInterstitial Lung DiseaseIdiopathic Interstitial PneumoniaIdiopathic Pulmonary FibrosisSarcoidosisRespiratory Bronchiolitis Associated Interstitial Lung DiseaseDesquamative Interstitial PneumoniaCryptogenic Organizing PneumoniaAcute Interstitial PneumonitisIdiopathic Lymphoid Interstitial PneumoniaIdiopathic Pleuroparenchymal Fibroelastosis
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