Treatment Trials

6 Clinical Trials for Various Conditions

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COMPLETED
Safety and Effectiveness of the PXL Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Position
Description

To determine whether the Peschke PXL-330 is safe and effective in the treatment of corneal thinning conditions.

COMPLETED
Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
Description

There is no standard of care medication regimen for the management of pain and inflammation post-corneal crosslinking (CXL), although most cornea specialists agree on use of an antibiotic and steroid eye drop in the immediate postoperative period. However, steroid tapering schedule and use of additional topical non-steroidal anti-inflammatory (NSAID) eyedrops vary amongst practitioners. The goal of this study is to compare postoperative pain scores between patients receiving a tapering dose of topical steroids over 1-month post-CXL, versus those receiving an intracanalicular dexamethasone insert.

RECRUITING
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking
Description

To determine whether the Peschke PXL-330 system is safe and effective in the treatment of corneal thinning conditions.

ENROLLING_BY_INVITATION
Corneal Biomechanical Analysis Using Brillouin Microscopy
Description

The objective of this study is to measure the Brillouin biomechanical properties in keratoconic corneas and characterize biomechanical alterations that occur after corneal procedures that inherently strengthen or weaken the cornea by evaluating the change in Brillouin metrics before and after treatments.

COMPLETED
Epi-On Corneal Crosslinking for Keratoconus
Description

Epithelium-On Corneal Crosslinking for Keratoconus.

UNKNOWN
Corneal Cross-Linking Comparing Variables
Description

The purpose of this study is to evaluate the Safety and Efficacy of Corneal Cross Linking in a Continuous Beam versus Pulsed Treatments across epithelium on and epithelium off surfaces.