Treatment Trials

3 Clinical Trials for Various Conditions

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RECRUITING
Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation
Description

The purpose of this study is to determine the safety and effectiveness (how well it works) of a new experimental ultrasound bath device that uses low frequency ultrasound (LFU) that may or may not help healing.

UNKNOWN
Effectiveness of KneeMD on Flexion Contracture in Total Knee Arthroplasty Patients
Description

The purpose of this study is to evaluate the effect of the KneeMD subject-controlled knee rehabilitation device on the incidence of postoperative flexion contracture.

UNKNOWN
Botulinum Toxin A to Treat Flexion Contracture After Total Knee Arthroplasty
Description

The goal of this research project is to evaluate injections of botulinum toxin A (Botox) as the treatment for knee flexion contracture after total knee arthroplasty (TKA). The current treatment for patients who do not achieve full extension of the knee (flexion contracture) after TKA consists of an aggressive physical therapy program, home stretching program, and the use of an extension orthosis (brace). Many patients do not tolerate wearing these braces. This initial project is designed to use injections of Botox as an adjunct to the standard current treatment and evaluate its efficacy. It is our hypothesis that a single injection into the hamstrings in addition to routine postoperative rehabilitation will result in improved knee extension and this improvement in function should endure without further treatment.