Treatment Trials

3 Clinical Trials for Various Conditions

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TERMINATED
Mechanical Intervention on the Scalp Microbiome: Setting the Stage for the Future Management of Cicatricial Alopecias
Description

The objective of this study is to assess the effect of standardized scalp care, specifically mechanical cleansing with the Venus Glow™ Device and water, on the scalp microbiome. This study also seeks to characterize the microbiome of the normal, healthy scalp, thereby providing a baseline for which the scalp affected by hair and scalp disease can be compared.

UNKNOWN
Design and Validation of a New Assessment Tool for Lichen Planopilaris
Description

The study's Primary Objective is to design and validate a grading system for objective and accurate assessment of lichen planopilaris. Secondary Objectives: * To assess change in symptoms such as pain and itch using a Numeric Rating Scale(NRS) scores and quality of life using the Dermatology Life Quality Index (DLQI) scores * To correlate this grading system with patient skin biopsies evaluating disease activity on a microscopic level * To correlate this grading system with digital global photography and trichoscopy

COMPLETED
Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris
Description

To evaluate the safety and efficacy of ixekizumab in lichen planus and lichen planopilaris clinical response by Total Body Surface (TBS) determination, Investigator Global Assessment (IGA) Score, Lichen Planopilaris Activity Index (LPPAI), and Frontal Fibrosing Alopecia Severity Score (FFASS).