Treatment Trials

12 Clinical Trials for Various Conditions

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      COMPLETED
      Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines
      Description

      The purpose of the study is to investigate the safety and duration of effect following different doses of Botulinum Toxin A (NT 201) in the treatment of glabellar frown lines (GFL).

      Conditions
      Moderate to Severe Glabellar Frown Lines
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      COMPLETED
      IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines
      Description

      The study objective is to show the superior efficacy of IncobotulinumtoxinA (Xeomin) over placebo by evaluation of treatment success analyzing the investigator's rating on the Facial Wrinkle Scale and the patient's assessment on a 4-point scale. 255 female and male patients with moderate to severe glabellar frown lines will be randomized in a 2:1 ratio to receive one injection of IncobotulinumtoxinA (Xeomin) or placebo and will be followed up until day 120.

      Conditions
      Moderate to Severe Glabellar Frown Lines
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      COMPLETED
      IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines No. 2
      Description

      The study objective was to show the superior efficacy of IncobotulinumtoxinA (Xeomin) over placebo by evaluation of treatment success analyzing the investigator's rating on the Facial Wrinkle Scale and the patient's assessment on a 4-point scale. 255 female and male patients with moderate to severe glabellar frown lines to be randomized in a 2:1 ratio to receive one injection of IncobotulinumtoxinA (Xeomin) or placebo and will be followed up until day 120.

      Conditions
      Moderate to Severe Glabellar Frown Lines
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      COMPLETED
      Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines
      Description

      The purpose of this study is to investigate the safety and efficacy of NT 201 (active ingredient: Botulinum (neuro)toxin type A, free from complexing proteins) in the combined treatment of wrinkles in the upper face (Upper Facial Lines \[UFL\]): Horizontal Forehead Lines \[HFL\], Glabellar Frown Lines \[GFL\], and Lateral Canthal Lines \[LCL\]). It is a prospective, randomized, double-blind, placebo-controlled, multicenter study with a placebo-control main period (MP) followed by an open-label extension (OLEX) period.

      Conditions
      Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
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      COMPLETED
      Assess Aesthetic Improvement With QM1114-DP in Subjects With Moderate to Severe Lateral Canthal Lines and Glabellar Lines
      Description

      This study to assess aesthetic improvement following treatment with QM1114-DP.

      Conditions
      Glabellar Frown LinesCanthal Lines
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      COMPLETED
      Assess Aesthetic Improvement and Onset of QM1114-DP in Subjects With Moderate to Severe Glabellar Lines
      Description

      The objective of this study is to evaluate the aesthetic improvement and onset of QM1114-DP treatment for subjects with moderate to severe glabellar lines

      Conditions
      Glabellar Frown Lines
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      COMPLETED
      Treatment of Moderate to Severe Glabellar Lines
      Description

      The objective of the study is to evaluate the efficacy and safety of a single dose of QM1114-DP compared to placebo for the treatment of moderate to severe GL.

      Conditions
      Glabellar Frown Lines
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      COMPLETED
      Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination
      Description

      This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

      Conditions
      Glabellar Frown Lines (GL)Lateral Canthal Lines (LCL)
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      COMPLETED
      Efficacy and Safety of DaxibotulinumtoxinA for Injection to Treat Moderate to Severe Glabellar Lines
      Description

      This is a safety and efficacy study of DaxibotulinumtoxinA for Injection to treat moderate to severe frown lines.

      Conditions
      Glabellar Frown Lines
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      COMPLETED
      Efficacy and Safety of DaxibotulinumtoxinA for Injection to Treat Moderate to Severe Glabellar Lines
      Description

      This is a safety and efficacy study of DaxibotulinumtoxinA for Injection to treat moderate to severe frown lines.

      Conditions
      Glabellar Frown Lines
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      COMPLETED
      Safety of Single and Repeat Treatments of DaxibotulinumtoxinA for Injection for Treatment of Moderate to Severe Glabellar Lines
      Description

      This is a long term safety study of DaxibotulinumtoxinA for Injection for the treatment of moderate to severe glabellar lines following single and repeat administration.

      Conditions
      Glabellar Frown Lines
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      COMPLETED
      Patient Satisfaction Study of BOTOX® Cosmetic in the Treatment of Moderate to Severe Frown Lines
      Description

      This was a pilot study to observe patient satisfaction with BOTOX® Cosmetic treatment in glabellar rhytides (frown lines) using a new treatment satisfaction measure.

      Conditions
      Glabellar Frown Lines
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