Treatment Trials

4 Clinical Trials for Various Conditions

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      COMPLETED
      Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout
      Description

      A Phase IIA, open-label, multicenter, active-controlled, parallel-group clinical trial designed to evaluate the safety and efficacy of two doses of Bucillamine compared with low-dose Colchicine in the treatment of patients with acute gout flare.

      Conditions
      Gout
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      COMPLETED
      Tranilast Plus Allopurinol in Patients With Moderate to Severe Gout (TAnGO)
      Description

      This Phase 2 study will be a multicenter, double-blind, randomized, active-comparator study to evaluate the safety and efficacy of tranilast in combination with allopurinol in patients with hyperuricemia and moderate to severe gout.

      Conditions
      Moderate to Severe GoutHyperuricemia
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      COMPLETED
      Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment
      Description

      The purpose of this study is to determine the effect of febuxostat, once daily (QD) or twice daily (BID), on renal function in gout patients with elevated serum urate levels and who have moderate to severe renal impairment.

      Conditions
      Renal Impairment
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      COMPLETED
      Mild, Moderate and Severe Renal Impairment Study
      Description

      This is a Phase 1, single-dose, open-label, pharmacokinetic (PK) and pharmacodynamic (PD) study of RDEA3170 in adult male subjects with mild, moderate, and severe renal impairment.

      Conditions
      Gout
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