Treatment Trials

2 Clinical Trials for Various Conditions

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      ACTIVE_NOT_RECRUITING
      Study Evaluating Zenocutuzumab in Patients with or Without Molecularly Defined Cancers
      Description

      This is a Phase II, open-label, 2-arm, multicenter, international study designed to evaluate the efficacy of zenocutuzumab alone or in combination in patients with the following diagnoses: Group A: NRG1+ NSCLC Group B: mCRPC

      Conditions
      NSCLC Harboring NRG1 FusionMetastatic Castration-resistant Prostate Cancer
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      ACTIVE_NOT_RECRUITING
      A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)
      Description

      This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immunogenicity and anti-tumor activity of zenocutuzumab (MCLA-128) in patients with solid tumors harboring an NRG1 fusion (eNRGy)

      Conditions
      Solid Tumours Harboring NRG1 FusionNSCLC Harboring NRG1 FusionPancreatic Cancer Harboring NRG1 FusionNRG1 Fusion
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