Treatment Trials

4 Clinical Trials for Various Conditions

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ACTIVE_NOT_RECRUITING
Study of Chemoimmunotherapy for High-Risk Neuroblastoma
Description

The purpose of this study is to find out whether an experimental drug called Hu3F8 can be given with the chemotherapy drugs irinotecan and temozolomide and another drug called GM-CSF. The investigators want to find out if this combination is safe and what effect it has on the participant and the disease.

COMPLETED
A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma
Description

The purpose of this study is to assess the safety and tolerability profile of TB-403 (humanized monoclonal antibody against placental growth factor (PlGF)) in pediatric subjects with relapsed or refractory Medulloblastoma.

RECRUITING
A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma
Description

The purpose of this study is to test which treatment schedule of β-glucan with bivalent vaccine is more effective for participants with high-risk neuroblastoma that is in complete remission.

ACTIVE_NOT_RECRUITING
A Study of N9 Chemotherapy in Children With Neuroblastoma
Description

The purpose of the study is to find out whether N9 is a safe and effective treatment for children with neuroblastoma. N9 includes 3 different combinations of chemotherapy drugs that are given at different times - Cyclophosphamide, topotecan, and vincristine (CTV), Ifosfamide, carboplatin, and etoposide (ICE), Cyclophosphamide, doxorubicin, and vincristine (CDV).