Treatment Trials

4 Clinical Trials for Various Conditions

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      TERMINATED
      Nonrestorative Sleep RSQ (Restorative Sleep Questionnaire) Development-- Methodology Study
      Description

      To begin to refine development of the RSQ (Restorative Sleep Questionnaire) measure in subjects with NRS (Nonrestorative Sleep) by generating item content pertaining to morning refreshment and uncovering problems in instrument administration in subjects with nonrestorative sleep

      Conditions
      Nonrestorative Sleep
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      COMPLETED
      A Double-blind, Parallel Group, Placebo-Controlled Outpatient Trial of PD 00200390 in Adults With Nonrestorative Sleep
      Description

      In a Phase II trial in subjects with nonrestorative sleep, PD 0200390 demonstrated a positive treatment effect relative to placebo on the primary endpoint, the weekly version of the Restorative Sleep Questionnaire (RSQ-W). In this study, the dose-response relationship of varying doses of PD 0200390 using the Restorative Sleep Questionnaire (RSQ-W), will be explored in Nonrestorative Sleep subjects.

      Conditions
      Nonrestorative Sleep
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      COMPLETED
      Subjective Study to Assess the Efficacy of APD125 in Patients With Sleep Maintenance Insomnia
      Description

      This study is designed to compare 2 doses of APD125 (20 mg and 40 mg) with placebo in otherwise healthy adults with primary insomnia primarily with complaints of maintaining sleep. Participants will be required to maintain a daily sleep dairy for up to 3 weeks while on study.

      Conditions
      Primary Insomnia
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      COMPLETED
      A Study To Investigate The Absorption, Metabolism And Excretion Of [14C] PD 0200390 In Six Healthy Male Volunteers
      Description

      To determine the mass balance of PD 0200390

      Conditions
      Insomnia
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