Treatment Trials

2 Clinical Trials for Various Conditions

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      RECRUITING
      Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
      Description

      This is a standard of care treatment guideline for allogeneic hematopoetic stem cell transplant (HSCT) in patients with primary immune deficiencies.

      Conditions
      SCIDOmenn's SyndromeReticular DysgenesisWiskott-Aldrich SyndromeBare Lymphocyte SyndromeCommon Variable ImmunodeficiencyChronic Granulomatous DiseaseCD40 Ligand DeficiencyHyper IgM SyndromeX-linked Lymphoproliferative DiseaseHemophagocytic LymphohistiocytosisGriscelli SyndromeChediak-Higashi SyndromeLangerhan's Cell Histiocytosis
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      COMPLETED
      Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders
      Description

      The primary objective is to determine the feasibility of attaining acceptable rates of donor cell engraftment (\>25% donor chimerism at 180 days) following reduced intensity conditioning (RIC) regimens in pediatric patients \< 21 years receiving cord blood transplantation for non-malignant disorders.

      Conditions
      Non Malignant DisordersImmunodeficienciesCongenital Marrow FailuresHemoglobinopathiesInborn Errors of MetabolismSickle CellThalassemiaLysosomal Storage Disease
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