Treatment Trials

3 Clinical Trials for Various Conditions

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      COMPLETED
      A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects
      Description

      The purpose of the study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics (PK) of sirolimus after single dose administration.

      Conditions
      Healthy SubjectsPharmacokinetics of IsavuconazolePharmacokinetics of Sirolimus
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      RECRUITING
      Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
      Description

      This is a phase 1, multi-center, open-label, dose-escalation study of nab-sirolimus in adult patients with locally advanced or metastatic solid tumors and moderate hepatic impairment or normal hepatic function.

      Conditions
      Tumor, SolidTumorAdvanced Solid Tumor
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      ACTIVE_NOT_RECRUITING
      OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
      Description

      To evaluate the pharmacokinetic parameters of sirolimus release from the Svelte DES.

      Conditions
      Acute Coronary Syndrome
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