Treatment Trials

3 Clinical Trials for Various Conditions

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      TERMINATED
      A Study to Evaluate Safety and Efficacy of Panobinostat in Participants With Primary Myelofibrosis
      Description

      This study assessed the safety and efficacy of Panobinostat as a single agent in the treatment of Primary Myelofibrosis, Post-Polycythemia Vera and Post-Essential Thrombocythemia. There were two cohorts - participants with JAK2 mutation and participants without JAK2 mutation.

      Conditions
      Primary MyelofibrosisPost-Polycythemia VeraPost-Essential Thrombocytopenia
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      TERMINATED
      Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia
      Description

      Phase 3, randomized, controlled study to evaluate the safety and efficacy of oral pacritinib compared to Best Available Therapy (BAT) in patients with thrombocytopenia and primary or secondary myelofibrosis.

      Conditions
      Primary MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
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      TERMINATED
      Pacritinib Versus Best Available Therapy to Treat Myelofibrosis
      Description

      Phase 3, randomized, controlled study to evaluate the safety and efficacy of oral pacritinib compared to Best Available Therapy (BAT) in patients with primary or secondary myelofibrosis.

      Conditions
      Primary MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
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