Treatment Trials

5 Clinical Trials for Various Conditions

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      RECRUITING
      PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9
      Description

      The purpose of this study is to find the highest safe dose of hu5B1-TCO and the best dosing schedule of hu5B1-TCO and 64Cu-Tz-SarAr for finding cancer cells that are CA19-9 positive. This study will also help to find out how much radiation the body is exposed to when 64Cu-Tz-SarAr is used, and provide information on the way the body absorbs, distributes, and gets rid of 64Cu-Tz-SarAr.

      Conditions
      Pancreatic CancerPancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal AdenocarcinomaPrimary Pancreatic Ductal AdenocarcinomaMetastatic Pancreatic Cancer
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      UNKNOWN
      Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study
      Description

      The purpose of this study is to assess the interobserver agreement (IOV) for pancreatico-biliary Volumetric Laser Endomicroscopy (VLE) de-identified clips using the new VLE criteria. This is an Interobserver study to validate VLE criteria for indeterminate biliary and pancreatic duct strictures and evaluate impact on clinical management.

      Conditions
      Biliary StricturePancreas CancerCholangiocarcinomaBile Duct CancerBile Duct Neoplasms MalignantBile Duct NeoplasmsBile Duct LesionsBile Duct ObstructionBile Duct DiseasesBile Duct Obstruction, ExtrahepaticBile Duct StenosiBile Duct AdenomaPancreatic Duct StricturePancreatic Duct StenosisPancreatic Duct ObstructionPancreatic Ductal AdenocarcinomaPrimary Sclerosing Cholangitis
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      COMPLETED
      Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer
      Description

      Phase I trial to study the effectiveness of vaccine therapy with or without sargramostim in treating patients who have advanced or metastatic cancer. Vaccines may make the body build an immune response to kill tumor cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow or peripheral blood. Combining vaccine therapy with sargramostim may make tumor cells more sensitive to the vaccine and may kill more tumor cells

      Conditions
      Adenocarcinoma of the ColonAdenocarcinoma of the GallbladderAdenocarcinoma of the PancreasAdenocarcinoma of the RectumAdult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerCholangiocarcinoma of the GallbladderDiffuse Adenocarcinoma of the StomachIntestinal Adenocarcinoma of the StomachMale Breast CancerMixed Adenocarcinoma of the StomachOvarian Endometrioid AdenocarcinomaPaget Disease of the Breast With Intraductal CarcinomaPaget Disease of the Breast With Invasive Ductal CarcinomaRecurrent Adult Primary Liver CancerRecurrent Breast CancerRecurrent Colon CancerRecurrent Gallbladder CancerRecurrent Gastric CancerRecurrent Malignant Testicular Germ Cell TumorRecurrent Pancreatic CancerRecurrent Rectal CancerRecurrent Salivary Gland CancerSalivary Gland AdenocarcinomaStage II Malignant Testicular Germ Cell TumorStage II Pancreatic CancerStage III Colon CancerStage III Gastric CancerStage III Malignant Testicular Germ Cell TumorStage III Pancreatic CancerStage III Rectal CancerStage III Salivary Gland CancerStage IIIA Breast CancerStage IIIB Breast CancerStage IV Breast CancerStage IV Colon CancerStage IV Gastric CancerStage IV Pancreatic CancerStage IV Rectal CancerStage IV Salivary Gland CancerThyroid Gland Medullary CarcinomaUnresectable Gallbladder Cancer
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      COMPLETED
      Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer
      Description

      RATIONALE: Vaccines made from a person's white blood cells that have been treated in the laboratory may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy in treating patients who have advanced or metastatic cancer.

      Conditions
      Breast CancerColorectal CancerGallbladder CancerGastric CancerHead and Neck CancerLiver CancerOvarian CancerPancreatic CancerTesticular Germ Cell Tumor
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      COMPLETED
      An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
      Description

      Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy. The tissue obtained will be used to determine how these tumor blood vessels respond to radiation therapy delivered to the tumor, after it has been removed. This radiation is delivered in the research lab. This research is being conducted in order to develop new methods to treat tumors by radiation therapy. No additional surgery will be performed to obtain these samples, and only materials that remain after all diagnostic testing has been completed will be used.

      Conditions
      Ovarian NeoplasmsColorectal NeoplasmsMelanomaSmall Cell Lung CancerLiposarcoma
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