Treatment Trials

6 Clinical Trials for Various Conditions

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RECRUITING
Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)
Description

1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.

Conditions
ACTIVE_NOT_RECRUITING
Mitigating Post-Op RV Dysfunction After LVAD Implantation
Description

This project evaluates right ventricle (RV) protective strategies after left ventricular assist device (LVAD) implantation.

ACTIVE_NOT_RECRUITING
Paceport Swan-Ganz Data Collection Study
Description

In association with Edwards LifeSciences, the study will aim to develop an algorithm based on right heart (right atrial, right ventricular and pulmonary artery) waveforms for the early detection of RV dysfunction in cardiothoracic and liver surgery patients at UMMC. This is a prospective, non-interventional, observational study.

Conditions
RECRUITING
Impella RP Flex with Smart Assist
Description

To capture observational data of the Abiomed Impella RP Flex in a real-world setting.

COMPLETED
Temporary Biventricular Pacing
Description

The hypothesis of this study is that temporary biventricular pacing will improve hemodynamic performance in patients with right ventricular dysfunction after open cardiac chamber cardiac surgery.

RECRUITING
TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR
Description

Three-dimensional echocardiography has become a gold standard to assess right ventricular (RV) function, and investigators plan to use 3D transesophageal echocardiography to assess RV function in 3 types of aortic valve replacement (AVR): surgical AVR (SAVR), mini-sternotomy AVR (mini AVR), and transcatheter AVR (TAVR).