Treatment Trials

2 Clinical Trials for Various Conditions

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      RECRUITING
      Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia
      Description

      The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or NPM1-m acute leukemia based on safety and pharmacokinetics (PK).

      Conditions
      Relapsed/Refractory KMT2A-r Acute LeukemiaRelapsed/Refractory NUP98-r Acute LeukemiaRelapsed/Refractory NPM1-m Acute Leukemia
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      RECRUITING
      A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
      Description

      A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in adult patients with acute leukemia.

      Conditions
      Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, Acute
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