Treatment Trials

2 Clinical Trials for Various Conditions

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      TERMINATED
      MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies
      Description

      This research study tests a new medicine for mobilizing stem cells so they can be collected and used for allogeneic stem cell transplant for treatment of hematological malignancies. MGTA-145, the new medicine, will be given with plerixafor.

      Conditions
      Related Donors Donating PBSC to a Family MemberHealthy DonorsAcute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome
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      COMPLETED
      A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor
      Description

      This is a Phase II, open-label, two strata, multicenter, prospective study of plerixafor-mobilized HLA-identical sibling allografts in recipients with hematological malignancies. This study will establish the safety and efficacy of subcutaneous plerixafor for this purpose.

      Conditions
      Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family MemberAcute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic SyndromeChronic Myelogenous LeukemiaNon-Hodgkin's LymphomaHodgkin's DiseaseChronic Lymphocytic Leukemia
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