Treatment Trials

4 Clinical Trials for Various Conditions

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      COMPLETED
      Microneedle Patch Study in Healthy Infants/Young Children
      Description

      Microneedles can be prepared as a low-cost patch that is simple for patients to apply for vaccine delivery targeting the many antigen-presenting cells present in the skin. Data regarding the safety, reactogenicity, tolerability, and acceptability of a microneedle patch in children are lacking. The goal of this study is to evaluate the safety, reactogenicity, and acceptability of placement of a placebo microneedle patch to the skin of children.

      Conditions
      VaccinationSkin Absorption
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      COMPLETED
      A Study Evaluating the Absorption Of Varenicline Through The Skin Following Once Daily Application Of A Patch For 14 Days
      Description

      This study will evaluate the steady-state pharmacokinetics, safety and tolerability of a varenicline patch applied once daily to the skin for 14 days.

      Conditions
      Smoking Cessation
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      COMPLETED
      A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
      Description

      To estimate the absorption, safety, and tolerability of a dimebon transdermal solution relative to the dimebon immediate release oral formulation.

      Conditions
      Alzheimer's DiseaseHuntington's Disease
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      COMPLETED
      A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Solution And A Varenicline Patch Applied To The Skin
      Description

      To evaluate the absorption, safety, and tolerability of a varenicline solution and a varenicline patch applied to the skin.

      Conditions
      Smoking Cessation
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