RECRUITING

Genetics of Cardiovascular and Neuromuscular Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Official Title

Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.

Quick Facts

Study Start:1996-09
Study Completion:2026-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00138931

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.
  1. * Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

Contacts and Locations

Study Contact

Lisa Dellefave, MS
CONTACT
773-702-4310
Ldellefa@medicine.bsd.uchicago.edu
Elizabeth McNally, MD PhD
CONTACT
773-702-2679
emcnally@uchicago.edu

Principal Investigator

Elizabeth McNally, MD PhD
PRINCIPAL_INVESTIGATOR
University of Chicago

Study Locations (Sites)

University of Chicago
Chicago, Illinois, 60637
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Elizabeth McNally, MD PhD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date1996-09
Study Completion Date2026-01

Study Record Updates

Study Start Date1996-09
Study Completion Date2026-01

Terms related to this study

Keywords Provided by Researchers

  • Cardiomyopathy
  • Arrhythmia
  • Muscular Dystrophy

Additional Relevant MeSH Terms

  • Cardiomyopathy
  • Arrhythmia
  • Muscular Dystrophy