Genetics of Cardiovascular and Neuromuscular Disease

Description

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Conditions

Cardiomyopathy, Arrhythmia, Muscular Dystrophy

Study Overview

Study Details

Study overview

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.

Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.

Genetics of Cardiovascular and Neuromuscular Disease

Condition
Cardiomyopathy
Intervention / Treatment

-

Contacts and Locations

Chicago

University of Chicago, Chicago, Illinois, United States, 60637

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.
  • * Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Elizabeth McNally, MD PhD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

2026-01