RECRUITING

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Description

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Study Overview

Study Details

Study overview

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Condition
Chronic Prostatitis (CP)
Intervention / Treatment

-

Contacts and Locations

Boston

Boston Children's Hospital (BCH), Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Have symptoms for at least 3 months within the preceding 6 months:
  • * Pain in the pelvic area
  • * Urinary frequency and/or
  • * Urinary urgency and/or
  • * Sexual dysfunction (erectile dysfunction)
  • * Have CP/CPPS, Interstitial Cystitis (IC), Bladder Pain Syndrome BPS, or Bladder Fasciculation Syndrome (BFS)
  • * Be willing to provide a blood/saliva, bladder tissue (from previous biopsy) and urine sample
  • * Agree to complete several brief questionnaires
  • * Family member of someone with CP/CPPS, BPS, IC or BFS
  • * Live in the USA or Canada
  • * Major structural/anatomical urinary tract abnormalities
  • * Underlying inborn or congenital conditions which affect the urinary tract
  • * Surgery/chemotherapy in the pelvic area
  • * Bacterial cause to CP/CPPS or recurrent Urinary tract infections (UTI)
  • * Traumatic cause to CP/CPPS

Ages Eligible for Study

to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Boston Children's Hospital,

Catherine Brownstein, PhD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital

Study Record Dates

2026-12-31