RECRUITING

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Official Title

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Quick Facts

Study Start:2007-01-15
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00499317

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Have symptoms for at least 3 months within the preceding 6 months:
  2. * Pain in the pelvic area
  3. * Urinary frequency and/or
  4. * Urinary urgency and/or
  5. * Sexual dysfunction (erectile dysfunction)
  6. * Have CP/CPPS, Interstitial Cystitis (IC), Bladder Pain Syndrome BPS, or Bladder Fasciculation Syndrome (BFS)
  7. * Be willing to provide a blood/saliva, bladder tissue (from previous biopsy) and urine sample
  8. * Agree to complete several brief questionnaires
  9. * Family member of someone with CP/CPPS, BPS, IC or BFS
  10. * Live in the USA or Canada
  1. * Major structural/anatomical urinary tract abnormalities
  2. * Underlying inborn or congenital conditions which affect the urinary tract
  3. * Surgery/chemotherapy in the pelvic area
  4. * Bacterial cause to CP/CPPS or recurrent Urinary tract infections (UTI)
  5. * Traumatic cause to CP/CPPS

Contacts and Locations

Study Contact

Elicia Estrella, MS, LCGC
CONTACT
617-919-4552
elicia.estrella@childrens.harvard.edu

Principal Investigator

Catherine Brownstein, PhD
PRINCIPAL_INVESTIGATOR
Boston Children's Hospital

Study Locations (Sites)

Boston Children's Hospital (BCH)
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Boston Children's Hospital

  • Catherine Brownstein, PhD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2007-01-15
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2007-01-15
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • Urgency
  • Frequency
  • Pelvic pain
  • Sexual dysfunction
  • Erectile dysfunction
  • Painful intercourse

Additional Relevant MeSH Terms

  • Chronic Prostatitis (CP)
  • Chronic Pelvic Pain Syndrome (CPPS)
  • Painful Bladder Syndrome (PBS)
  • Benign Frequency Syndrome (BFS)
  • Interstitial Cystitis