RECRUITING

Autologous Stem Cell Transplantation for Crohn's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC) in pediatric and adult patients with severe Crohn's disease.

Official Title

Autologous Stem Cell Transplantation With CD34-Selected Peripheral Blood Stem Cells (PBSC) in Pediatric and Adult Patients With Severe Crohn's Disease

Quick Facts

Study Start:2012-06-26
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT00692939

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Shawna H McIntyre, RN
CONTACT
412-692-5552
mcintyresm@upmc.edu

Principal Investigator

Paul Szabolcs, MD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

UPMC Prebyterian- Adult Gastroenterology
Pittsburgh, Pennsylvania, 15213
United States
Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team
Pittsburgh, Pennsylvania, 15224
United States

Collaborators and Investigators

Sponsor: Paul Szabolcs

  • Paul Szabolcs, MD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2012-06-26
Study Completion Date2026-12

Study Record Updates

Study Start Date2012-06-26
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Stem cell transplantation
  • Crohn's Disease

Additional Relevant MeSH Terms

  • Crohn's Disease