The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC) in pediatric and adult patients with severe Crohn's disease.
Crohn's Disease
The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC) in pediatric and adult patients with severe Crohn's disease.
Autologous Stem Cell Transplantation for Crohn's Disease
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UPMC Prebyterian- Adult Gastroenterology, Pittsburgh, Pennsylvania, United States, 15213
Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team, Pittsburgh, Pennsylvania, United States, 15224
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
10 Years to 60 Years
ALL
No
Paul Szabolcs,
Paul Szabolcs, MD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh
2026-12