RECRUITING

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

Official Title

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Quick Facts

Study Start:2011-06
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01243931

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm.
  1. * Inability to give informed consent
  2. * Inability to maintain stable fixation for OCT imaging
  3. * Inability to commit to required visits to complete the study
  4. * Deep corneal opacities and irregularities
  5. * Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery

Contacts and Locations

Study Contact

Humberto Martinez, COT
CONTACT
503-494-7712
martinhu@ohsu.edu
Denny Romfh, OD
CONTACT
503-494-4351
romfhd@ohsu.edu

Principal Investigator

David Huang, MD, PhD
PRINCIPAL_INVESTIGATOR
Casey Eye Institute, Oregon Health & Science University

Study Locations (Sites)

Casey Eye Institute, Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • David Huang, MD, PhD, PRINCIPAL_INVESTIGATOR, Casey Eye Institute, Oregon Health & Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2011-06
Study Completion Date2026-12

Study Record Updates

Study Start Date2011-06
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Phototherapeutic keratectomy
  • Optical coherence tomography
  • Corneal opacity
  • Corneal dystrophy

Additional Relevant MeSH Terms

  • Corneal Opacity