Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Description

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

Conditions

Corneal Opacity

Study Overview

Study Details

Study overview

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Condition
Corneal Opacity
Intervention / Treatment

-

Contacts and Locations

Portland

Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm.
  • * Inability to give informed consent
  • * Inability to maintain stable fixation for OCT imaging
  • * Inability to commit to required visits to complete the study
  • * Deep corneal opacities and irregularities
  • * Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

David Huang, MD, PhD, PRINCIPAL_INVESTIGATOR, Casey Eye Institute, Oregon Health & Science University

Study Record Dates

2026-12