RECRUITING

Investigation of Anatomical Correlates of Speech Discrimination

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of the inner ear and auditory neurons on speech discrimination performance in quiet and in noise. This information may be used as a predictor of hearing aid benefit. The investigators expect to find decreased speech understanding ability resulting from both loss of sensory cells and the loss of auditory neurons.

Official Title

Investigation of Anatomical Correlates of Speech Discrimination

Quick Facts

Study Start:2013-01
Study Completion:2026-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01781039

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Normal hearing to moderate sensorineural hearing loss
  2. * Sufficient English proficiency to complete speech discrimination testing in English
  1. * Hearing loss less than a 45 dB HL pure tone average (average hearing thresholds at 500, 1000 and 2000 Hz)
  2. * Conductive hearing loss
  3. * Neurodegenerative disease

Contacts and Locations

Principal Investigator

Mark Parker, PhD
PRINCIPAL_INVESTIGATOR
Steward St. Elizabeth's Medical Center

Study Locations (Sites)

Steward St. Elizabeth's Medical Center
Brighton, Massachusetts, 02135
United States

Collaborators and Investigators

Sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.

  • Mark Parker, PhD, PRINCIPAL_INVESTIGATOR, Steward St. Elizabeth's Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2013-01
Study Completion Date2026-08

Study Record Updates

Study Start Date2013-01
Study Completion Date2026-08

Terms related to this study

Keywords Provided by Researchers

  • "hair cell"
  • "hearing aid"
  • "hearing loss"
  • "auditory nerve"
  • synaptopathy
  • "Outer hair cell"
  • "Otoacoustic emission"

Additional Relevant MeSH Terms

  • Sensorineural Hearing Loss