RECRUITING

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

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Conditions

Scleroderma, LocalizedMorpheaFrontal Linear Scleroderma en Coup de SabreScleroderma, CircumscribedScleroderma, Linear

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Morphea in Adults and Children (MAC) cohort is the first registry for both children and adults with morphea (also known as localized scleroderma) in the country. The purpose of the registry is to learn more about morphea, specifically: * How morphea behaves over time * How frequently specific problems occur along with morphea (for example, arthritis) * Whether morphea has an autoimmune background

Official Title

Immunologic and Genetic Profiles in Subsets of Morphea Patients

Quick Facts

Study Start:2007-05
Study Completion:2028-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01808937

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Patient must have a clinical diagnosis of morphea confirmed by the primary investigator and by histopathological examination.
  2. 2. Ages 0-90 years old
  3. 3. Children must weigh more than 20 lbs. in order to satisfy Children's Medical Center policy for the maximum amount of blood drawn in a 24 hour period.
  4. 4. Patient or legal guardian must be able to speak and read at a 6th grade reading level.
  5. 5. Both male and female patients will be eligible
  6. 6. All races and ethnic backgrounds will be included
  7. 7. Relationships to proband: All patients with morphea will be included. A patient's family history will be reviewed and if there is a family history of morphea or systemic sclerosis then we will give the study patient the investigator's contact information and ask the family member to call the study team to answer any questions and enroll them in the study if they choose to do so.
  8. 8. Ability to give informed consent: Patients must be able to give informed consent or they will give assent with parent or guardian consent as a minor to be a part of the morphea registry.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Heidi Jacobe, MD, MSCS
CONTACT
214.633.1837
heidi.jacobe@utsouthwestern.edu

Principal Investigator

Heidi Jacobe, MD, MSCS
PRINCIPAL_INVESTIGATOR
University of Texas Southwestern Medical Center

Study Locations (Sites)

UT Southwestern Medical Center - Department of Dermatology
Dallas, Texas, 75390-9069
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

  • Heidi Jacobe, MD, MSCS, PRINCIPAL_INVESTIGATOR, University of Texas Southwestern Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2007-05
Study Completion Date2028-01

Study Record Updates

Study Start Date2007-05
Study Completion Date2028-01

Terms related to this study

Additional Relevant MeSH Terms

  • Scleroderma, Localized
  • Morphea
  • Frontal Linear Scleroderma en Coup de Sabre
  • Scleroderma, Circumscribed
  • Scleroderma, Linear