RECRUITING

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.

Official Title

Study to Identify Rare Genetic Variants Causing Severe Early Childhood Obesity

Quick Facts

Study Start:2014-02
Study Completion:2030-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01998750

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Known genetic causes of obesity
  2. * Known Endocrine causes of obesity.
  3. * Neurologic tumor, trauma or surgery
  4. * Prior malignancy or transplant
  5. * Known autoimmune diseases
  6. * Edema of a known or unknown cause
  7. * Prolonged steroid use.

Contacts and Locations

Study Contact

Vidhu Thaker, M.D.
CONTACT
212-851-5315
vvt2114@cumc.columbia.edu

Principal Investigator

Vidhu Thaker, M.D.
PRINCIPAL_INVESTIGATOR
Columbia University

Study Locations (Sites)

Boston Children's Hospital
Boston, Massachusetts, 02115
United States
Columbia University Medical Center
New York, New York, 10032
United States

Collaborators and Investigators

Sponsor: Columbia University

  • Vidhu Thaker, M.D., PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2014-02
Study Completion Date2030-12

Study Record Updates

Study Start Date2014-02
Study Completion Date2030-12

Terms related to this study

Keywords Provided by Researchers

  • obesity
  • genetics
  • early-onset
  • childhood

Additional Relevant MeSH Terms

  • Obesity