Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Description

This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.

Conditions

Obesity

Study Overview

Study Details

Study overview

This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.

Study to Identify Rare Genetic Variants Causing Severe Early Childhood Obesity

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Condition
Obesity
Intervention / Treatment

-

Contacts and Locations

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

New York

Columbia University Medical Center, New York, New York, United States, 10032

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Known genetic causes of obesity
  • * Known Endocrine causes of obesity.
  • * Neurologic tumor, trauma or surgery
  • * Prior malignancy or transplant
  • * Known autoimmune diseases
  • * Edema of a known or unknown cause
  • * Prolonged steroid use.

Ages Eligible for Study

to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Columbia University,

Vidhu Thaker, M.D., PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

2030-12