RECRUITING

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.

Official Title

Celiac Disease Genomic Environmental Microbiome and Metabolomic (CDGEMM) Study

Quick Facts

Study Start:2014-03
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02061306

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 6 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)
  2. * First-degree relatives of patients affected with biopsy-proven CD
  1. * Infants older than 6 months of age
  2. * Inability or unwillingness of legal guardian/representative to give written informed consent

Contacts and Locations

Study Contact

Victoria Kenyon, MHA
CONTACT
617-643-4366
vakenyon@mgb.org

Principal Investigator

Alessio Fasano, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital
Maureen M. Leonard, MD
STUDY_CHAIR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital for Children
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Alessio Fasano, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital
  • Maureen M. Leonard, MD, STUDY_CHAIR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2014-03
Study Completion Date2025-12

Study Record Updates

Study Start Date2014-03
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Celiac disease
  • coeliac disease
  • microbiome
  • gluten
  • infants
  • pregnancy
  • genetic

Additional Relevant MeSH Terms

  • Celiac Disease