RECRUITING

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.

Official Title

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

Quick Facts

Study Start:2013-06
Study Completion:2026-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02118922

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:20 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Have occludable narrow angles (without a patent peripheral iridotomy)
  2. * Monocular subjects
  3. * Do not or cannot understand the instructions for the imaging
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Fatima Clouser, MS
CONTACT
4077331679
fclouser@mgh.harvard.edu
Andy Yun, PhD
CONTACT
syun@partners.org

Principal Investigator

Andy Yun, PhD
PRINCIPAL_INVESTIGATOR
Masachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Andy Yun, PhD, PRINCIPAL_INVESTIGATOR, Masachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2013-06
Study Completion Date2026-09

Study Record Updates

Study Start Date2013-06
Study Completion Date2026-09

Terms related to this study

Keywords Provided by Researchers

  • LASIK

Additional Relevant MeSH Terms

  • Keratoconus
  • Ectasia
  • Crosslinking
  • Fuchs' Endothelial Dystrophy