A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

Description

We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.

Conditions

Keratoconus, Ectasia, Crosslinking, Fuchs' Endothelial Dystrophy

Study Overview

Study Details

Study overview

We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

Condition
Keratoconus
Intervention / Treatment

-

Contacts and Locations

Boston

Massachusetts General Hospital, Boston, Massachusetts, United States, 02114

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Have occludable narrow angles (without a patent peripheral iridotomy)
  • * Monocular subjects
  • * Do not or cannot understand the instructions for the imaging

Ages Eligible for Study

20 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Massachusetts General Hospital,

Andy Yun, PhD, PRINCIPAL_INVESTIGATOR, Masachusetts General Hospital

Study Record Dates

2026-09