RECRUITING

Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

Description

This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.

Conditions

Rheumatoid Arthritis (RA)
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Related Conditions:

Rheumatoid Arthritis (RA)

Study Overview

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Study Details

Study overview

This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.

Use of Acthar in Rheumatoid Arthritis Related Flares

Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

Condition
Rheumatoid Arthritis (RA)
Intervention / Treatment

-

Contacts and Locations

Los Angeles

UCLA David Geffen School of Medicine, Division of Rheumatology, Los Angeles, California, United States, 90095

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Patient must meet 1987 ACR criteria
  • 2. Age \> 18 years of age
  • 3. Baseline DAS28/Erythrocyte Sedimentation Rate (ESR) \>=3.2
  • 4. Stable concomitant Disease Modifying Anti-Rheumatic Drugs (DMARDs)
  • 5. Stable prednisone \<10mg or equivalent
  • 6. Power Doppler score of \>=10
  • 1. Prior treatment with Acthar in the past 2mos
  • 2. Meet one of the above RA flare requirements
  • 3. Subjects who have received live or live attenuated vaccines within 6 weeks prior to the first dose of study drug (or the zoster vaccine)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Veena Ranganath, MD, MS,

Veena K Ranganath, M.D., M.S., PRINCIPAL_INVESTIGATOR, University of California, Los Angeles

Study Record Dates

2025-12-31