RECRUITING

Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.

Official Title

Use of Acthar in Rheumatoid Arthritis Related Flares

Quick Facts

Study Start:2017-07-20
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02541955

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Patient must meet 1987 ACR criteria
  2. 2. Age \> 18 years of age
  3. 3. Baseline DAS28/Erythrocyte Sedimentation Rate (ESR) \>=3.2
  4. 4. Stable concomitant Disease Modifying Anti-Rheumatic Drugs (DMARDs)
  5. 5. Stable prednisone \<10mg or equivalent
  6. 6. Power Doppler score of \>=10
  1. 1. Prior treatment with Acthar in the past 2mos
  2. 2. Meet one of the above RA flare requirements
  3. 3. Subjects who have received live or live attenuated vaccines within 6 weeks prior to the first dose of study drug (or the zoster vaccine)

Contacts and Locations

Study Contact

Veena K Rangantah, M.D., M.S.
CONTACT
310-825-3061
vranganath@mednet.ucla.edu
Bal-lan Yen
CONTACT
310-206-4112
byen@mednet.ucla.edu

Principal Investigator

Veena K Ranganath, M.D., M.S.
PRINCIPAL_INVESTIGATOR
University of California, Los Angeles

Study Locations (Sites)

UCLA David Geffen School of Medicine, Division of Rheumatology
Los Angeles, California, 90095
United States

Collaborators and Investigators

Sponsor: Veena Ranganath, MD, MS

  • Veena K Ranganath, M.D., M.S., PRINCIPAL_INVESTIGATOR, University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-07-20
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2017-07-20
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Rheumatoid arthritis (RA)
  • Musculoskeletal ultrasound (MSUS)

Additional Relevant MeSH Terms

  • Rheumatoid Arthritis (RA)