RECRUITING

Pharmacogenomics of Heparin-Induced Thrombocytopenia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this research is to identify genomic markers that can predict heparin-induced thrombocytopenia (HIT), which is a very serious side effect to heparin. Heparin is commonly used to prevent blood clots and the investigators may be able to identify genomic markers which can be used to prevent heparin use in people who will get HIT.

Official Title

Pharmacogenomics of Heparin-Induced Thrombocytopenia

Quick Facts

Study Start:2016-03
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02717039

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age or older
  2. * Ability to give informed consent
  3. * Have undergone testing for heparin/PF4 antibody with or without SRA testing for HIT
  4. * Have received treatment with unfractionated heparin or low molecular weight heparin (enoxaparin, dalteparin, tinzaparin) prior to antibody or SRA testing
  1. * Less than 18 years of age
  2. * Pregnancy
  3. * Hemoglobin less than 9 mg/dL (for larger 5 ounce blood draw)
  4. * Known Human Immunodeficiency Virus (HIV) infection
  5. * Inability to give informed consent

Contacts and Locations

Study Contact

Jason H Karnes, PharmD, PhD
CONTACT
520-626-1447
karnes@pharmacy.arizona.edu
Talin A Robinson-Catalan, MS
CONTACT
520-278-6114
talinrobinson@arizona.edu

Study Locations (Sites)

Banner University Medical Center - Tucson
Tucson, Arizona, 85721
United States

Collaborators and Investigators

Sponsor: University of Arizona

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-03
Study Completion Date2026-07

Study Record Updates

Study Start Date2016-03
Study Completion Date2026-07

Terms related to this study

Additional Relevant MeSH Terms

  • Heparin-induced Thrombocytopenia