Pharmacogenomics of Heparin-Induced Thrombocytopenia

Description

The purpose of this research is to identify genomic markers that can predict heparin-induced thrombocytopenia (HIT), which is a very serious side effect to heparin. Heparin is commonly used to prevent blood clots and the investigators may be able to identify genomic markers which can be used to prevent heparin use in people who will get HIT.

Conditions

Heparin-induced Thrombocytopenia

Study Overview

Study Details

Study overview

The purpose of this research is to identify genomic markers that can predict heparin-induced thrombocytopenia (HIT), which is a very serious side effect to heparin. Heparin is commonly used to prevent blood clots and the investigators may be able to identify genomic markers which can be used to prevent heparin use in people who will get HIT.

Pharmacogenomics of Heparin-Induced Thrombocytopenia

Pharmacogenomics of Heparin-Induced Thrombocytopenia

Condition
Heparin-induced Thrombocytopenia
Intervention / Treatment

-

Contacts and Locations

Tucson

Banner University Medical Center - Tucson, Tucson, Arizona, United States, 85721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age or older
  • * Ability to give informed consent
  • * Have undergone testing for heparin/PF4 antibody with or without SRA testing for HIT
  • * Have received treatment with unfractionated heparin or low molecular weight heparin (enoxaparin, dalteparin, tinzaparin) prior to antibody or SRA testing
  • * Less than 18 years of age
  • * Pregnancy
  • * Hemoglobin less than 9 mg/dL (for larger 5 ounce blood draw)
  • * Known Human Immunodeficiency Virus (HIV) infection
  • * Inability to give informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Arizona,

Study Record Dates

2026-07