RECRUITING

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

Official Title

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Quick Facts

Study Start:2017-02-13
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03218137

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of premature ventricular contractions (PVCs)
  2. * Scheduled to undergo an electrophysiology study with the intention of performing cardiac ablation for the treatment of PVCs
  3. * Male or female between the ages of 18 and 70 years
  4. * Capable of giving informed consent
  1. * Any structural heart disease
  2. * Coronary artery disease (≥ 70% stenosis)
  3. * Current treatment with anti-arrhythmic drugs
  4. * Pregnant
  5. * Asthma (if administering adenosine)

Contacts and Locations

Study Contact

James E Ip, M.D
CONTACT
212 746 2158
jei9008@med.cornell.edu
Dolores T Reynolds, BSN
CONTACT
212 746 4617
dtr2001@med.cornell.edu

Principal Investigator

James E Ip, M.D
PRINCIPAL_INVESTIGATOR
Weill Medical College of Cornell University

Study Locations (Sites)

Weill Cornell Medicine
New York, New York, 10065
United States

Collaborators and Investigators

Sponsor: Weill Medical College of Cornell University

  • James E Ip, M.D, PRINCIPAL_INVESTIGATOR, Weill Medical College of Cornell University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-02-13
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2017-02-13
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Subjects
  • diagnosed

Additional Relevant MeSH Terms

  • Premature Ventricular Contraction (PVC)