RECRUITING

Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

(a) To explore the feasibility and utility of implementing broad preemptive pharmacogenomic result delivery in the inpatient setting across multiple institutions specifically with the goal of incorporating minority-specific pharmacogenomic information; (b) To determine whether clinical outcomes for the drug warfarin are improved in African Americans through the availability of pharmacogenomics-based dosing guidance at the point-of-care.

Official Title

Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

Quick Facts

Study Start:2017-11-09
Study Completion:2025-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03225820

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients must be at least 18 years of age.
  2. * Patients must self-identify as African American
  1. * Patients who have undergone, or are being actively considered for, liver or kidney transplantation.
  2. * Patients with known active or prior leukemia.
  3. * Inability to understand and give informed consent to participate.
  4. * For patients being recruited to the warfarin sub-study, those with a glomerular filtration rate or creatinine clearance \<30 mL/min34.

Contacts and Locations

Study Contact

Cancer Clinical Trials Office
CONTACT
1-855-702-8222
cancerclinicaltrials@bsd.uchicago.edu

Principal Investigator

Peter O'Donnell, MD
PRINCIPAL_INVESTIGATOR
University of Chicago

Study Locations (Sites)

The University of Illinois at Chicago
Chicago, Illinois, 60607
United States
Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Peter O'Donnell, MD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-11-09
Study Completion Date2025-08

Study Record Updates

Study Start Date2017-11-09
Study Completion Date2025-08

Terms related to this study

Keywords Provided by Researchers

  • pharmacogenomic information

Additional Relevant MeSH Terms

  • Information Seeking Behavior