Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

Description

(a) To explore the feasibility and utility of implementing broad preemptive pharmacogenomic result delivery in the inpatient setting across multiple institutions specifically with the goal of incorporating minority-specific pharmacogenomic information; (b) To determine whether clinical outcomes for the drug warfarin are improved in African Americans through the availability of pharmacogenomics-based dosing guidance at the point-of-care.

Conditions

Information Seeking Behavior

Study Overview

Study Details

Study overview

(a) To explore the feasibility and utility of implementing broad preemptive pharmacogenomic result delivery in the inpatient setting across multiple institutions specifically with the goal of incorporating minority-specific pharmacogenomic information; (b) To determine whether clinical outcomes for the drug warfarin are improved in African Americans through the availability of pharmacogenomics-based dosing guidance at the point-of-care.

Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

Implementation of Point-of-Care Pharmacogenomic Decision Support Accounting for Minority Disparities

Condition
Information Seeking Behavior
Intervention / Treatment

-

Contacts and Locations

Chicago

The University of Illinois at Chicago, Chicago, Illinois, United States, 60607

Chicago

Northwestern University, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients must be at least 18 years of age.
  • * Patients must self-identify as African American
  • * Patients who have undergone, or are being actively considered for, liver or kidney transplantation.
  • * Patients with known active or prior leukemia.
  • * Inability to understand and give informed consent to participate.
  • * For patients being recruited to the warfarin sub-study, those with a glomerular filtration rate or creatinine clearance \<30 mL/min34.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Peter O'Donnell, MD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

2025-08