Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Fluent in English
- * Diagnosis of PMD/PNES confirmed by a neurologist with expertise in movement disorders.
- * Per the treating neurologist, subject is unlikely to require treatment and/or dosage changes for 3-6 months following screening
- * Any history of a significant neurological disorder, which may interfere with the interpretation of study data, as determined by the PI
- * Chronic or progressive medical condition
- * Any history of traumatic brain injury or significant head trauma
- * Currently meets criteria for substance abuse or dependence
- * History of any psychotic disorder or other psychiatric condition which may interfere with data interpretation
- * Pregnancy
- * Metal or devices in the head, including neurostimulators or metal foreign bodies
- * Any other implanted metal device, including pacemaker, spinal cord stimulator, VNS.
- * Any other ferromagnetic substance in the body that may increase study risk (including dental prosthetics, etc.).
- * Taking tricyclic antidepressant or antiepileptic medications or CNS active drugs under "strong potential hazard" list in Rossi et al., 2009
- * Current diagnosis of any inflammatory or autoimmune disorder within last 6 months
- * Any history of traumatic brain injury or significant head trauma
- * Diagnosis of organic seizure disorder, including febrile seizures and tonic-clonic seizures;
- * Neurological disorder other than PMD and PNES including stroke, fainting spells or syncope of unknown cause(s);
- * Major or unstable medical illness, especially any current diagnosis of inflammatory or autoimmune disorders within last 6 months
- * Metal or devices in the head, including neurostimulators or metal foreign bodies
- * Taking tricyclic antidepressant medications or CNS active drugs under "strong potential hazard" list in Rossi et al., 2009;
- * Diagnosis of dementia, or Montreal Cognitive Assessment (MoCA) ≤24;
- * Recurrent visual hallucinations, within the past 6 months;
- * History of significant uncontrollable movements of the head;
- * Any clinically significant abnormality on vital signs
Ages Eligible for Study
18 Years to 65 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes