RECRUITING

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations. This randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.

Official Title

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Quick Facts

Study Start:2018-01-15
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03401762

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Hemiparesis from first ever stroke at least 6 months prior to screening
  2. * Severe motor impairment (FMA of 7-30)
  3. * At least some voluntary shoulder and elbow muscle activation.
  4. * Hemiparesis from first ever stroke within the past 21 days
  5. * Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors
  1. * Cognitive impairment with at least moderately impaired attention, or unable to follow instructions of the MCI task
  2. * Visual impairment (such as hemianopia) preventing full view of the screen
  3. * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest).
  4. * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
  5. * Inability to understand or follow commands in English due to aphasia or other reason
  6. * Diffuse or multifocal infarcts
  7. * Substantial arm pain preventing participation for 90 minutes a day
  8. * New spasticity treatment (pharmacological or Botox)

Contacts and Locations

Study Contact

Marc W Slutzky, MD, PhD
CONTACT
3125034653
mslutzky@northwestern.edu
Cynthia Gorski
CONTACT
cynthia.gorski@northwestern.edu

Study Locations (Sites)

Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-01-15
Study Completion Date2025-12

Study Record Updates

Study Start Date2018-01-15
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • rehabilitation

Additional Relevant MeSH Terms

  • Stroke
  • Stroke, Acute