Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Description

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations. This randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.

Conditions

Stroke, Stroke, Acute

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Study Overview

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Study Details

Study overview

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations. This randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern University, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Hemiparesis from first ever stroke at least 6 months prior to screening
  • * Severe motor impairment (FMA of 7-30)
  • * At least some voluntary shoulder and elbow muscle activation.
  • * Hemiparesis from first ever stroke within the past 21 days
  • * Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors
  • * Cognitive impairment with at least moderately impaired attention, or unable to follow instructions of the MCI task
  • * Visual impairment (such as hemianopia) preventing full view of the screen
  • * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest).
  • * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
  • * Inability to understand or follow commands in English due to aphasia or other reason
  • * Diffuse or multifocal infarcts
  • * Substantial arm pain preventing participation for 90 minutes a day
  • * New spasticity treatment (pharmacological or Botox)

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northwestern University,

Study Record Dates

2025-12